[Horse_Lover92]

What is wrong with him, I heard that a lot of people don't like him, Why?

Tex has impressive blood, his registered name is Impressive Mo Te

[Jess!]

Impressive was HYPP Postive.

Hypp is genetic mutation that only recently has been implicated in the rare but burgeoning - and sometimes fatal - muscular disorder known as hyperkalemic periodic paralysis

Hyperkalemic periodic paralysis is characterized by sporadic attacks of muscle tremors (shaking or trembling), weakness and/or collapse. Attacks can also be accompanied by loud breathing noises resulting from paralysis of the muscles of the upper airway. Occasionally, sudden death can occur following a severe paralytic attack, presumably from heart failure or respiratory muscle paralysis.

Attacks of HYPP can take various forms and commonly have been confused with other conditions. Because of the muscle tremors and weakness, HYPP often resembles exertional rhabdomyolysis ("tying-up" syndrome). "Tying-up" syndrome can be caused by many different circumstances, including exercising a horse beyond the capacity to which it has been trained, as well as nutritional deficiencies and metabolic diseases. A distinguishing feature of this disease from "tying-up" syndrome though, is that horses usually appear normal following an attack of HYPP. Horses with "tying-up" syndrome, on the other hand, tend to have a stiff gait and painful, firm muscles of the hind limbs, rump and/or back. "Tying-up" syndrome is also generally associated with some type of exercise. HYPP, by contrast, is not usually associated with exercise, but occurs when horses are at rest, at feeding time, or following a stressful event such as transport, feed changes, or concurrent illness.

Because a horse may be down and reluctant or unable to stand during an HYPP attack, many owners have thought their horses were experiencing colic. HYPP has also been confused with seizures due to the pronounced muscle trembling and collapse. Unlike seizures and other conditions that cause fainting, however, horses with HYPP are conscious and aware of their surroundings during an attack and do not appear to be in pain. Respiratory conditions and choke have also been confused with HYPP because some horses make loud breathing noises during an attack.

[Horse_Lover92]

So could anything be passed on to Tex

[Jess!]

Originally Posted by Horse_Lover92

So could anything be passed on to Tex

If he's registered, it should say on his papers whether or not he is HYPP N/N. It's a required test for those horses with impressive in their bloodlines.

[Sage_in_yellow]

Impressive is "nown" to be bad, but i have seen good little foals that coudnt sell because of this. We had one little foal who had all the potensial in the world fut no one would touch him because of his lines.

it really kind of sad

-Alix

[Appylvr]

Impressive has been linked to HYPP...

What is HYPP?

Hyperkalemic Periodic Paralysis Disease (HYPP) is a muscular disease that affects both horses and humans. It is caused by a hereditary genetic defect that disrupts a protein called a sodium ion channel, a tiny gateway in the membrane of muscle cells. The genetic defect disrupts the channel's normal opening and closing, such that uncontrolled sodium influxes occur. These influxes in turn change the voltage current of muscle cells, causing uncontrolled muscle twitching or profound muscle weakness. High levels of potassium in the blood usually are present when the disruptions in the ion channel occur.

What Are Effects of HYPP?

Horses with HYPP can experience unpredictable attacks of paralysis which, in severe cases, can lead to collapse and sudden death. The cause of death usually is cardiac arrest and /or respiratory failure. The disease is characterized by intermittent episodes of muscle tremors manifested by generalized or localized shaking, trembling and weakness. Occasionally, episodes are accompanied by respiratory noises resulting from paralysis of the muscles of the upper airway (larynx and pharynx). In cases of mild attacks, muscle tremors may be so subtle as to be detectable only by an experienced clinician performing EMG testing.

Can Symptoms of HYPP Vary in Severity?

Clinical signs of HYPP do vary widely among different horses. Homozygous horses are affected more severely than heterozygous horses. Under ideal management practices, the defective gene does not appear to have adverse effects, but stress and/or increased potassium in the serum can trigger clinical signs of muscle dysfunction. Why some horses manifest severe signs of the disease and other exhibit little or no signs is unknown but currently under investigation. Unfortunately, a horse carrying the defective gene but showing minimal signs has the same chance of passing the gene to future generations as does the affected horse with severe signs.

What is the Origin of the Genetic Defect Causing HYPP?

The original genetic defect causing HYPP was a natural mutation that occurred as part of the evolutionary process. The majority of such mutations, which are constantly occurring, are not compatible with survival. However, the genetic mutation causing HYPP produced a functional, yet altered, sodium ion channel. This gene mutation is not a product of inbreeding. The gene mutation causing HYPP inadvertently became widespread when breeders sought to produce horses with heavy musculature.

Is HYPP Limited To A Particular Bloodline of Horses?

HYPP is associated with horses of heavy musculature, but this does not mean that all horses with well developed musculature are afflicted with the disease. The mutant gene causing HYPP presently has been identified in the descendents of the horse "Impressive." Research has not yet been performed on other bloodlines to ascertain whether the same or similar genetic mutation existing in other bloodlines also may cause HYPP. Since "Impressive" descendants are so numerous, the genetic mutation in the bloodline is widespread. Theoretically, it is possible that other mutations causing HYPP in different bloodlines may be more difficult to identify because they are not so widespread. HYPP is unique in that it is the first equine disease in which breeding and molecular genetics have yielded a specific genetic mutation identifiable with a named bloodline. It only is a matter of time before other heritable conditions in various bloodlines likewise can be identified.

[Horse_Lover92]

What age do they get the test, I am going to check his papers

[Jess!]

Originally Posted by Horse_Lover92

What age do they get the test, I am going to check his papers

Usually as foals. I bought a yearling that was already tested, and had HYPP N/N on his papers.

[Solsalia]

Did he have hypp? n/h or h/h? I love the impressive breed horses but I want them hypp n/n

Originally Posted by Sage_in_yellow

Impressive is "nown" to be bad, but i have seen good little foals that coudnt sell because of this. We had one little foal who had all the potensial in the world fut no one would touch him because of his lines.

it really kind of sad

-Alix

[Horse_Lover92]

I can't tell, I don't think it says, how much is it to test him. I am going to scan his papers