Discuss Has anyone ever dealt with purpura hemorrhagica? at the Horse Health forum - Horse Forums. Ive been off for a long time. But I have a huge issue. My son ...
Has anyone ever dealt with purpura hemorrhagica?
Ive been off for a long time. But I have a huge issue. My son came home with a horse and 5 days later full blown strangles. Got over it within a week all looking good. Then one night he looked as though someone had filled him up with water. He couldnt walk, had temp of 105 and totally miserable. Vet called prognosis purpura hemorrhagica. He is up and down goos one time bad the next.
Anyone ever dealt with this and had good results. If so whats your treatment. Right now he is on 35 cc of penicillan 2x daily, as of now 5cc of dex 1x daily, banimine, and gastroguard and probios.
Solid swellings have turned to soft edemas.
Poor guy he is soooo miserable and help would be appreciated.
A freind is god's way of saying you will never walk alone!
Yes several years ago I had a yearling come down with it. We followed basically the same treatment as you are. It's important to keep up with the banimine and dex. The swelling in my colt was so bad the skin split on his legs but he came through it ok. He will always have some interesting scaring and some minor hock damage but was eventually completely sound. I ended up selling him as a three year old and have since lost track of his progress but last I heard he was competing successfully as a hunter.
Purpura hemorrhagica is an aseptic necrotizing vasculitisin blood vessel walls...
characterized primarily by edema and petechial or ecchymotic
hemorrhage. Although the exact pathogenesis of purpura
hemorrhagica is not fully understood, it appears to be
a vasculitis caused by the deposition of immune complexes
The severity of clinical signs seen with purpura varies
from a mild, transient reaction to a severe, fatal disease.
The typical clinical signs seen as a result of the vasculitisoccur. In some cases, the vasculitis may affect other sites
include subcutaneous edema, most frequently involving the
head, limbs, and/or trunk, and petechiation and ecchymoses
of the mucous membranes. Severe edema may result in oozing
from the skin surfaces, and sloughing of the skin may
such as the gastrointestinal tract, lungs, and muscle, resultingsoreness.
in signs such as colic, respiratory difficulties, and muscle
Corticosteroids are the primary treatment for purpura.
Generally, dexamethasone at 0.1–0.2 mg/kg followed by a
tapering dose regime is used. In those cases where purpura
is associated with active bacterial infection or the horse is
considered at high risk of developing infection, appropriate
antibiotic therapy is also indicated. Nonsteroidal anti-inflammatory
drugs may be of some benefit in some cases of
purpura. Supportive care, including intravenous fluids, hydrotherapy,
and bandaging may also be indicated. The majority
of the 53 horses with purpura were treated for more
than 7 days.
Purpura hemorrhagica can be a serious complication of
strangle. One of the 4 cases with purpura was euthanized
due to the severity of the skin necrosis.
1 Similarity, 3 of 22
horses with purpura secondary to exposure to S equi did
From the ACVIM Consensus statement on Strangles
Licensed Veterinary Technician, TX
Member American Assoc. of Equine Veterinary Technicians
Yea I have read everythign i could find on it. Still on dex and still swelling everytime we lower the dose. Worried about the length on the steroids.
I got a paint gelding out of the kill pens getting ready to head off to slaughter in Mexico. He came down with purpura which I would assume is a resulting complication from his recent environment. Swelling, temperature, skin splitting, open sores, huge sotmach lumps -- the works. 102 degrees in the shade here and flys are everywhere, any tiny scratch in the skin makes for a fly fest so keeping flys off and skin from getting infected is an additional (and overwhelming) challenge. All I can suggest is aggressive and immediate treatment, be militant about cleaning and spraying wounds, keep stalls and paddocks spotless and stay in touch with your vet to monitor progressive daily and be ready to address any new complications. Hose off swollen areas with cold water 2 x day and make sure they have clean, soft bedding to lay on as they ( and their legs) recover. I do not know what his prognosis will be, but the dex, penicillin shots and above steps are helping ~
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