View Poll Results: Which one do you give to your horse(s)?

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  • Adequan

    4 66.67%
  • Acetyl-D

    1 16.67%
  • Other

    1 16.67%
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Discuss Adequan vs. Adequan Compound (Acetyl-D) at the Horse Health forum - Horse Forums.

A little over 7 weeks ago I started my horse on what I thought was ...
  1. #1
    Senior Member southern_horse's Avatar
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    Question Adequan vs. Adequan Compound (Acetyl-D)

    A little over 7 weeks ago I started my horse on what I thought was Adequan. Turns out it's the Adequan Compound, Acetyl-D Glucosamine. I was a little confused at first about this, because the vet that had perscribed it to me, said it was actually Adequan. She wasn't exactly straight forwarded. I called her up for clarification and an explanation. Anyway, once I found out that actual Adequan is around $60 a month, I decided to just stick with the compound. She said that it is basically the same thing as Adequan, just not as quick to take effect. She told me that many of her clients use the compound and are quite happy with it.

    Is anyone else giving their horse Acetyl-D injections once a month? Is it working for your horse(s)? What do you think of it?

    EZ will be getting his first monthly vaccination coming up soon for his mild arthritis.
    my gold is in the form of a palomino - EZ <33


  2. #2
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    She's lying to you, or just don't know better.

    It is absolutely NOT even close to "basically the same thing", and truly, I'd be tempted to report her for misleading you up front.

    How is she even calling it "Adequan Compound"? There is Adequan, and there is not-Adequan which covers a wide range of things.

    Adequan is polysulfated glucosaminoglycan. Not even remotely close to acetyl-d glucosamine.

    Adequan is around $300 for 7 vials. How much that ends up being a month depends on whether you use it monthly, every other week, or just a loading dose 1-2 times a year.

    Take this FWIW
    http://www.wedgewoodpetrx.com/learni...inary-use.html
    Only one study has been done comparing Acetyl-D-Glucosamine to the FDA-approved PSGAG product, Adequan®. This study was funded by Luitpold, the manufacturer of Adequan and presented at the American Association of Equine Practioners (AAEP) conference in 2004. In this study, Acetyl-D-Glucosamine was found not to be as effective as Adequan at the conventional dose and treatment interval. The author of the study said that while products such as Acetyl-D- Glucosamine are "likely" to have a "positive effect on injured or diseased equine joints," the work has not been done to determine an appropriate dose or treatment regime.
    Yes, the study was done by the owners of Adequan. I don't know the details of the study and how the effectiveness was determined. If it was purely based on the changes to the cartilage, that's pretty objective and not much open for interpretation. If it was done based on reduction of lameness issues, that can get fuzzy.

    Here's another study, apparently after the above, or the above author didn't know about it
    http://www.j-evs.com/article/S0737-0...006-2/abstract
    which states that Adequan was significantly more effective than either acetyl-d glucosamine or chondroitin monosulfate.

    Does that mean NO horse receives ANY benefit? Nope
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    I would also be FURIOUS if my vet misled me like that!!

    my vet worked on the original trial of Adequan and is a FIRM believer in it. I've asked him about the so called "generic adequan", poly-glycan, etc... and he told me flat out "don't waste your money"

    He said in the adequan trials and his many, MANY years of being a lameness specialist, he said Adequan works better if done in the series as it's recommended (1 shot every 4 days, for a series of 7 injections)
    Standing at Stud -
    "The Ultimate Version" aka "Harley" ( Good Version x Zippos Tinky Poo) unshown due to injury, but full brother to the famous mare "A Good Poo", earner of over $40,000 in Western Pleasure and #24 on the LIFETIME leading NSBA horse's list

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    Senior Member goldiesmom's Avatar
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    ^^^ Agree! I too was told to not even bother with the "generic adequan" because it would be a waste of money! JBandRio is right there is Adequan and then there is everything else, and she's ripping you off if she's telling you it is!
    ~Melissa~

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    Senior Member southern_horse's Avatar
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    Well there is no way that I can afford $700 for the *real* deal

    My horse has been on MSM for a couple of years now, and I really couldn't see a difference in his performance.

    If the Acetyl-D doesn't work, then what would?

    What would be an affordable alternate?

    And yes I was quite upset about that fact that she wasn't straight forward with me. I was not educated about Adequan vs the "so called compound". I talked to my primary vet about the issue and she took the time to explain it all to me. Although she didn't say that the Acetyl-D wouldn't work...
    my gold is in the form of a palomino - EZ <33


  6. #6
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    Quote Originally Posted by southern_horse View Post
    Well there is no way that I can afford $700 for the *real* deal

    My horse has been on MSM for a couple of years now, and I really couldn't see a difference in his performance.

    If the Acetyl-D doesn't work, then what would?

    What would be an affordable alternate?

    And yes I was quite upset about that fact that she wasn't straight forward with me. I was not educated about Adequan vs the "so called compound". I talked to my primary vet about the issue and she took the time to explain it all to me. Although she didn't say that the Acetyl-D wouldn't work...
    a series of adequan is not $700. i just received the Dover catalog and the series of 7 shots if only $289.99 and you can buy them individually for $43.99 (you just need a prescription from your vet)

    if your vet quoted you $700 for real Adequan AND sold you the other stuff telling you it was a "compound of adequan"... i personally would be getting a new vet.
    Standing at Stud -
    "The Ultimate Version" aka "Harley" ( Good Version x Zippos Tinky Poo) unshown due to injury, but full brother to the famous mare "A Good Poo", earner of over $40,000 in Western Pleasure and #24 on the LIFETIME leading NSBA horse's list

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    Where are you getting $700 from?

    There is no comparison among MSM, acetyl-d glucosamine, and Adequan.

    Some horses do well on MSM, at least for a while.
    Some horses do well on acetyl, at least for a while.
    some horses do well on other knock-off "Adequan" products, at least for a while.

    Many do not do well on just those, either alone or in combination.

    Many horses DO do well on Adequan in some form, either a 1-2 yearly 7-shot series, or a 7-shot series followed by monthly shots, or something like that.

    Some horses do well on a better feed through like Cosequin or Corta-flex

    Sometimes you end up going straight, or eventually, to joint injections.

    It's very much an art, but an art based on science
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    Senior Member+ Preppy_Ponies's Avatar
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    As has been said they are not the same thing. And really don't work the same. I've tried Acetyl-D in the past and haven't had much luck with it. In the end it was a waste of money imo. Using real Adequan is worth it for a lot of horses. It's made a big difference for my old guy!

    The exact cost per month could vary depending on the horse but for a lot of them one shot every 4 weeks works well. And on that plan you're looking at spending $38-$45/month depending on where and how you buy it. And I would also recommend doing a loading dose to start out properly if you can which runs about $280-300 and then try the once a month plan after that.

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    Senior Member southern_horse's Avatar
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    Quote Originally Posted by Preppy_Ponies View Post
    As has been said they are not the same thing. And really don't work the same. I've tried Acetyl-D in the past and haven't had much luck with it. In the end it was a waste of money imo. Using real Adequan is worth it for a lot of horses. It's made a big difference for my old guy!

    The exact cost per month could vary depending on the horse but for a lot of them one shot every 4 weeks works well. And on that plan you're looking at spending $38-$45/month depending on where and how you buy it. And I would also recommend doing a loading dose to start out properly if you can which runs about $280-300 and then try the once a month plan after that.
    Well like I stated above, there is no way that I can afford that right now. And my horse isn't having extreme problems yet...just mild arthritis from aging.

    In the mean time, is there not something else that I can use to "take the edge off"
    my gold is in the form of a palomino - EZ <33


  10. #10
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    i see you are using MSM, you didn't mention a joint supplement. i would start there. i like acti-flex because it has some pretty high levels of everything (except MSM, i add extra) and it works out to only be about $.55 per day.

    i AM a firm believer in adequan. i had a mare that got one once a month. i didn't even have to keep track on a calendar, by week 3 i could tell she was due. i ran across a forum member selling some last fall for a good deal ( 5 for $185) so i bought them and they are in my fridge to use this coming spring.
    Standing at Stud -
    "The Ultimate Version" aka "Harley" ( Good Version x Zippos Tinky Poo) unshown due to injury, but full brother to the famous mare "A Good Poo", earner of over $40,000 in Western Pleasure and #24 on the LIFETIME leading NSBA horse's list

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